Abstract: 

With the development and application of precision medicine, its derivative ethical issues have become increasingly apparent. However, domestic research on precision medicine ethics is very limited. A systematic review of international precision medicine ethics research is helpful to provide theoretical references for domestic research. Based on the SSCI database, CiteSpace software is used to analyze the knowledge graph of the international precision medical ethics literature. The research has led to the following conclusions. (1) Basic research in disciplines such as biomedical ethics, big data medical ethics, and medical management and policy together constitutes the knowledge base of the current international precision medicine ethics research. (2) The current hot frontiers of international precision medicine ethics research mainly include topics such as precision medicine’s scientific research ethics, distribution justice, privacy protection, and public ethical attitudes. (3) In the future, precision medicine ethics research can explore research objects from general to specific, explore research methods from norms to empirical research, and seek theoretical innovation from ethics to management.

Key Words: 

Precision medicine ethics; Knowledge graph; CiteSpace; Big data