Abstract: Anglo-American epistemology is the mainstream of epistemology in today’s world, and has been spread all over the world. However, this epistemology expressed in English is not a universal epistemology that can be unconditionally adapted to any other language. The concept of “local knowledge” and the most universal and objective knowledge of physics, mathematics and logic are all local, which provides a preliminary proof for the locality of Anglo-American epistemology. “The argument from that the translation of English knowledge verbs cannot be standardized” and “the argument from given dependence of knowledge attribution” can prove strong proof for the locality of Anglo-American epistemology. The locality of Anglo-American epistemology demands us that: it is theoretically feasible and necessary to study and construct the epistemology or even Chinese philosophy based on Chinese expressions, and that the introduction of other cultures needs to be in some given.

Key Words: Anglo-American epistemology; Locality; Universality; Given